
Moreover, many non-human animals (probably including some insects) have a capacity to suffer pain and enjoy pleasure, but that fact does not necessarily preclude killing them, for they do not have the moral status of persons. So sentience seems neither necessary nor sufficient for a being to have full moral worth.
In addition, some people have more sentience than others, and a person can become more or less sentient. As Christopher Kaczor observes, "The kung fu master can put his arms around a burning cauldron ... The proverbial princess cannot stand the pea under her multiple mattresses." If moral worth depends on sentience, then some people are more valuable than others, and a person can become more or less valuable and deserving of respect.
Consider a clear-cut example: A man gets in a car accident and suffers permanent brain damage, but not enough to prevent him from functioning as a typical member of society. Nevertheless, some of his mental faculties have been slightly diminished. If those mental faculties are what confer moral worth, then he has become less valuable and less deserving of protection from being killed.
If this conclusion is false -- as anyone committed to the basic equality of all persons must hold -- then it is not true that moral worth depends upon having sentience, much less a brain or central nervous system. (Go here to learn about the only rationally sustainable basis for moral worth.)